Posters

      CSEO – The Cigarette Smoke Exposure Ontology

      Ansari, S.; Younesi, E.; Guendel, M.; Ahmadi, S.; Coggins, C.; Hoeng, J.; Hofmann-Apitius, M.; Peitsch, M.

      Conference date
      Apr 7, 2013
      Conference name
      Biocuration 2013
      Link to more information
      Topic
      Summary

      In the past years, significant progress has been made in the development and use of settings for collection of experimental data on tobacco exposure and the diseases induced by it. Despite the growing number of such data, there has been no community wide effort to facilitate the centralization and integration of tobacco exposure data scattered throughout a range of disparate sources. Moreover, to fulfill the aim of exposure and disease impact studies, it is of utmost importance to more reliably and efficiently establish the causal link to disease. Ontologies are structural frameworks for organizing knowledge, enabling information retrieval, and supporting data integration, data analysis, and exchange of knowledge within the community. Cigarette smoke exposure ontology (CSEO) was developed which is a specialized ontology with particular focus on the cigarette smoke exposure and related various experimental systems. Combining efforts of domain experts as well as novel computational methods, the ontology successfully describes exposure related terminology ranging from the scope and design definition of an experiment to its outcome with link to molecular events and ultimately to disease. After several iterations between the computational and domain expert groups, CSEO encompasses more than 20.000 concepts and classes. This ontology is represented in web ontology language (owl) format and is made freely available to the community through several channels. 

      PMIScience.com is operated by Philip Morris International for the purpose of publishing and disseminating scientific information about Philip Morris International’s efforts in support of its smoke-free product portfolio. This site is a global site for use by scientists, the public health and regulatory communities, and other stakeholders with an interest in tobacco policy. The purpose of this site is not advertising or marketing, nor is it directed at any specific market. It is not intended for use by consumers. New tobacco products sold in the United States are subject to FDA regulation; therefore the content of this site is not intended to make, and nor should it be construed as making, any product related claims in the United States without proper FDA authorization. ​
      ​
      Reduced Risk Products ("RRPs”) is the term we use to refer to products that present, are likely to present, or have the potential to present less risk of harm to smokers who switch to these products versus continuing smoking. PMI has a range of RRPs in various stages of development, scientific assessment and commercialization. All of our RRPs are smoke-free products that deliver nicotine with far lower quantities of harmful and potentially harmful constituents than found in cigarette smoke.